Gcsf-Chr19 Promotes Neutrophil Migration to Damaged Tissue through Blood Vessels in Zebrafish

Zebrafish to Damaged Tissue through Blood Vessels in Gcsf-Chr19 Promotes Neutrophil Migration

Cxcl8b and Cxcr2 Regulate Neutrophil Migration through Bloodstream in Zebrafish

Neutrophils play an essential role during an inflammatory response, which is dependent on their rapid recruitment from the bone marrow to the vasculature. However, there is no information about the molecular signals that regulate neutrophil entry to circulation during an inflammatory process in humans. This is mainly due to the lack of a suitable model of study that contains similar set of mole...

Neutrophil Reverse Migration Becomes Transparent with Zebrafish

The precise control of neutrophil-mediated inflammation is critical for both host defense and the prevention of immunopathology. In vivo imaging studies in zebrafish, and more recently in mice, have made the novel observation that neutrophils leave a site of inflammation through a process called neutrophil reverse migration. The application of advanced imaging techniques to the genetically trac...

Development of artificial blood vessels through tissue engineering

Background Cardiovascular diseases are one of the main causes of mortality in many parts of the world, with atherosclerosis figuring as the principal cause of coronary occlusion, stroke and aortic aneurysm [1]. Saphenous vein is the most commonly used vascular prosthesis for small-caliber (< 6 mm) vascular grafts, however, 10%-40% of patients do not have a saphenous vein suitable for prosthetic...

Tissue Engineering for Blood Vessels

The artificial vascular grafts currently in clinical use still have problems with respect to late calcification, restenosis, antithrombotic property, durability, biocompatibility, and safety, and no ideal artificial vascular graft has been developed to date. In view of this, we have been continuing basic experimental studies and their clinical applications in an attempt to develop tissue-engine...